Acute Kidney Injury in Patients Receiving Systemic Treatment for Cancer: A Population-Based Cohort Study

In a population-based cohort study of 163,071 patients aimed at uncovering acute kidney injury incidence data and risk factors among patients with cancer undergoing systemic therapy, researchers found that myeloma and leukemia were two of the malignancies with the highest 5-year AKI incidence (26.0% and 15.4%, respectively). The higher risk among leukemia patients may be attributable to sepsis, volume depletion, and tumor lysis syndrome. Data also showed decreased risk for AKI among patients receiving a bortezomib-based treatment regimen for myeloma.

Journal of the National Cancer Institute